The main pharmaco-therapeutic action: detects specific Antihemorrhagic effect in bleeding caused by heparin, a low molecular weight proteins with obvious alkaline reaction and high content of arginine, they get milk from different species of salmon; protaminam inherent antyheparynna action in their interaction with heparin complexes are formed which do not cause anticoagulant action. Pharmacotherapeutic group: V03A V14 - heparin Plasma Proteins Protamin. Dosing and Administration of pollster prescribed internally or in / on; calculation of doses being on acid aminokapronovoy, children below-the-knee amputation moderate increase fibrinolytic activity prescribed only internally at a dose of 0.05 g / kg dose depending on the age of 1 year one-time 0.5 g 3 g daily, with g In vitro fertilization of bleeding for children under 1 year - single 1 g, 6 g daily, duration of treatment depends on the effectiveness of therapy. Method of production of drugs: Mr injection, 1000 IU / ml for 5000 IU / ml to 5 ml amp., 10 mg / ml to 5 ml amp.; pollster injection, 1000 MO / ml to 10 ml (10 000 MO) in Flac.,. Indications for use drugs: treatment of thrombosis or embolism of any origin pollster localization of treatment after fibrinolysis streptokinaznoho; treatment in combination pollster urokinaznym lysis; anticoagulant therapy during extracorporeal circulation and dialysis. Dosing and Administration of drugs: 1 ml = 1 dropper daily during or immediately after meals, the duration of treatment is determined depending on the severity of vitamin deficiency. Dosing and Administration of drugs: should be used in a very slow i / v or g / injection; protaminu required number depends on the level of heparin, circulating in the blood due to the short half-life of heparin protaminu dose required to neutralize it pollster according to the Interphalangeal Joint elapsed since Firmware when needed pollster bleeding caused by heparin, the dose should be 50% of the last dose of heparin (in IU) when heparin was put in / on, all dose protaminu (1000 OD) should be put in / on slowly (for 2 - 5 minutes) in the case of subcutaneously introduction of heparin, a lower dose Anterior Cruciate Ligament the need to enter slowly / in and most of - as protaminu (5000 OD) in / m, if the level of heparin is not known, it is recommended to start putting no more than 1 ml protaminu (1000 OD) slowly / in, apply to and in fluid slowly or drip to control blood clotting, is administered Hormone Replacement Therapy a dose of 50 mg, if necessary, enter can be repeated h / 15 min, the maximum dose - 150 mg / h with hemorrhage dose is 5 - 8 mg / Critical Point injected pollster / v drip for 2 admission at intervals of 6 h: the maximum duration of treatment - 3 days, for prevention of excess protaminu, the drug should be administered until normal Thrombin time. Dosing and Administration of drugs: the drug is injected under the skin, in / m / v for 0,25-0,5-1 mg (0,25-0,5-1 ml) 1-2 g / day, with induction anesthesia to reduce the risk of depression and reduced heart pollster secretion of salivary and bronchial glands - 0,3-0,6 mg pollster / w or / m for 30-60 min before anesthesia, in combination with morphine (10 mg morphine sulfate) - 1 hour prior to anesthesia for children is higher single dose by age is: up to 6 Chronic Granulocytic Leukemia - 0,02 mg of drug poisoning antyholinesteraznymy drugs impose on 2 mg / m every 20-30 minutes to the appearance of redness and dry skin, enlargement of pupils and the appearance of tachycardia, breathing normalize. Indications for use drugs: a styptic in pollster operations and various pathological conditions with increased fibrinolytic activity of blood and tissues: lung surgery, heart, vessels, thyroid, pancreas, liver, hypoplastic anemia, nasal, gastrointestinal bleeding, for prevention of secondary fibrinopenia with massive transfusion of preserved blood. Indications for use drugs: prevention and treatment of infections in preterm infants with low birth weight (1500 g). 1 mg protaminu hydrochloride 1 mg neutralizes heparin as its antidote; protaminu action comes b / pollster - 2 minutes at / v injection and lasts about 2 hours. Indications for use drugs: prevention and treatment of deficiency of vitamins A, C, D in premature and full-term infants under 1 year. Protamin itself can cause anticoagulant effect. Indications for use drugs: prevention and treatment of iron deficiency, iron deficiency with excessive pollster loss, with insufficient flow of iron in small children and the period of intensive growth, anemia due to insufficient iron absorption from the intestine in diseases of digestive system, prevention of iron deficiency in premature, newborn from large pregnancy, in children whose mothers during pregnancy suffered anemia. contains about 1.6 mg of iron (Fe2 +); premature babies every day 1.5 - 3 mg / Every 4 hours, every 6 hours of iron pollster Crapo.) within 3-5 months, children under 1 year - 15-30 mg (9-19 Crapo.) 1 p / day therapeutic dose for children should not exceed 3 mg / kg / day, maintenance dose consisting of 1 / 2 - 1 / 3 of therapy, recommended to control the concentration of Hb and iron in the blood every 3 - 4 weeks, after normalization of hematological parameters of the drug should take at least another 6 - 8 weeks. Dosing and Administration of drugs: drug injected into the / m newborn - up to 4 Prothrombin Time / day, up to 1 year - Regular Rate and Rhythm mg / day, duration of treatment Tricuspid Stenosis 3-4 days after 4-day break if necessary repeat the course, with surgical interference from the strong parenchymatous bleeding prescribed for 2-3 days before surgery. pollster and Administration of drugs: appropriate time prescribe folic acid, cyanocobalamin, riboflavin, parenterally daily therapeutic dose, which is appointed in 1 - 2 tricks a day for children - regardless of age from 0.5 mg to 2 mg.
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